Biology at Work

Tecan Infinite® M1000 - top class performance with premium quad4 monochromators™
The Infinite M1000 is ideal for those researchers who like the flexibility and the ease-of-use of a monochromator-based
instrument and also demand top-class performance comparable to filter-based microplate readers. The Infinite M1000
joins the Infinite 200 and Infinite F500 family of detection systems and its new technology makes it the successor to
Tecan’s high performance Safire2™ microplate reader. Its power and versatility, combined with Tecan’s expertise as a
market leader in lab automation, will prepare you for all your future findings.
The Infinite M1000 is Tecan’s new, multimode, premium quad4 monochromators- based flagship microplate reader. It
has been specifically designed and built with the highest quality components and detection modules to ensure optimum
performance, robustness and innovation for even the most demanding researchers in drug discovery, the life science
industry and advanced research institutions, who continuously push the limits of today’s detection assays.
Tecan Infinte® M1000 passed the validation criteria under the following conditions: Excitation wavelength equaled 635 nm with a 5 nm bandwidth; emission wavelength equaled 670 nm with a 20nm bandwidth; instrument was set to 1 flash, and settle time equaled 50 ms. These settings yielded a Z' >0.7 in 1:09 minutes
Optimizing Performance of the Transcreener ADP2 Assay for the Tecan Infinte® M1000 Microplate Reader
A detailed scientific presentation of the instrument validation.
High performance features of the Tecan Infinte® M1000
- Premium quad4 monochromators.
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Z-focusing in all top reading modes (fluorescence Intensity, fluorescence polarization, luminescence) -
significantly improves the quality of your data measurements and makes it easy to optimize the set-up for varying
assay parameters (e.g. low volumes; different well shapes). -
User selectable frequency modes (patented) - in the fluorescence mode to choose between 'high sensitivity' and
'high speed' settings to adjust for your particular assay demands. -
Fast ratiometric measurements – immediate changes in wavelength in (TR)-FRET based assays and instant change
of polarization direction for FP measurements. - Free definition of plate formats - up to 1,536 wells.
- Top and bottom reading - for a variety of microplate formats in the fluorescence mode.
- On-board control buttons – for instant start/stop control of your pre-programmed measurement workflows at the touch of a button on your instrument, a convenient tool for routine applications.
- Modular design - allows upgrades to new detection modes at any time if further applications are required
- New optional luminescence module – provides access to single and dual color luminescence measurements, glow and flash luminescence with three fibers adapted for 96-well, 384-well and 1,536-well plates.
- Optional injectors – with variable syringe size, volume and speed settings.
- Optional stacker module - batch processing of up to 50 microplates.
- i-control™ software – for convenient workflow-oriented reader control.
Click here to access Tecan's Website, where you will find Application Notes and other information about the Tecan Infinite® M1000.

