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Transcreener® Posters

Transcreener® ADP2 Assay
Transcreener® ADP Assay
Transcreener® AMP/GMP Assay
Transcreener® GDP Assay
Transcreener® EPIGEN Assays
Transcreener® UDP Assay

 

Transcreener® ADP2 Assay

  1. Comparison of ADP Detection Methods used for High Throughput Screening (SLAS 2013)
  2. Transcreener®ADP2Assays: Streamlining Inhibitor Profiling for Kinases with Diverse ATP Requirements (MIPTEC 2010)

  3. ADP Detection in FP, TR-FRET and FI Assay Formats: Versatile Kinase/ATPase Detection Without the Use of Coupling Enzymes (SBS 2010)

  4. ADP Detection in FP, TR-FRET and FI Assay Formats: Versatile Kinase/ATPase Detection without the Use of Coupling Enzymes (Screening Europe, 2010)

  5. Utility of Hybrid Multi-Mode Readers using Both Monochromator- and Filter-Based Detection Capabilities as Demonstrated with Fluorescence Polarization,  Time-Resolved Fluorescence Resonance Energy Transfer, and Fluorescence Intensity    Assays for the Measurement of ADP (Lab Auto 2010)

  6. Improved Versatility of the Transcreener® ADP2 Assay: Alternative Fluorescence Detection Modes for All Major Instrument Platforms (Protein Kinase Target, 2009)

  7. Transcreener® ADP2 TR-FRET Red Assay: Homogeneous ADP Detection (SBS 2009)

  8. Targeting Low Activity ATP-utilizing Enzymes with the Improved Transcreener® ADP2 FP Assay (SBS 2009)

  9. Detecting ATP-utilizing Enzyme Activity Using a Simple Fluorescence Intensity Quenching ADP Assay (SBS 2009)

  10. Robust Detection of ATP-Utilizing Enzymes with an Improved Fluorescence Polarization ADP Detection Assay (Screening Europe 2009)

  11. Volume Scaling of the Transcreener® ADP2 FP Assay on the BioTek Synergy™ 2 and 4 Multi-Mode Microplate Readers Allows For Easy Transition From Assay Development to High-Throughput Screening (ALA 2009)

  12. Generating Better Biology Through the Use of BellBrook Labs’ Transcreener® ADP2 FP Assay and the BMG LABTECH PHERAstar Plus (ALA 2009)

  13. Demonstration of the Next Generation Transcreener® ADP2 FP Assay on the Tecan Safire2™ Microplate Reader (ALA 2009)

  14. Generate Improved Fluorescence Polarization Screening Results on PerkinElmer’s EnVision® Microplate Reader Through the Use of the Transcreener® ADP2 FP Assay (ALA 2009)

 

Transcreener® ADP Assay

  1. Beyond Kinases: Interrogating the Purinome (Keystone 2010)

  2. Optimizing Performance of the Transcreener ADP Assay for Commonly Used Multiwell Readers (SBS 2008)

  3. Application of the Transcreener Kinase Assay Platform in Evaluating PI3 Lipid Kinases (SBS 2007)

  4. Expanding Transcreener Assay Technology: ADP Detection using TR-FRET
  5. Interrogating Diverse Target Families by Homogenous Immunodetection of Nucleotides (Glyco 2007)

  6. Interrogation of Protein Phosporylation, Ubiquitination and Sumoylation Pathways Using Adenine Nucleotide Detection Assay (cell Signaling 2007)

  7. ADP Detection Assay for Diverse Kinases and ATPases

  8. A Robust and Flexible HTS Kinase Assay Using ADP Detection

  9. Simplifying Kinase Profiling using ADP Detection with the Transcreener Kinase Assay

  10. Screening Covalent Regulatory Enzymes: Glycosyltransferases, Sulfotransferases, Phosphodiesterases and other Emerging Targets (powerpoint of tutorial presented at SBS 2006)

 

Transcreener® AMP/GMP Assay

  1. Monitoring flux through the Sumoylation pathway using the Transcreener AMP/GMP assay (Keystone 2009)

  2. Application of theTranscreener AMP/GMP Assay for Interrogating Ubiquitinylation Cascades (SBS 2008)

  3. Homogenous AMP and GMP Detection : Applications in Drug Discovery (SBS 2007)

  4. Interrogation of Protein Phosporylation, Ubiquitination and Sumoylation Pathways Using Adenine Nucleotide Detection Assay (Cell Signaling 2007)

  5. Transcreener PDE Assay: Homogenous AMP and GMP Detection

  6. Screening Covalent Regulatory Enzymes: Glycosyltransferases, Sulfotransferases, Phosphodiesterases and other Emerging Targets (powerpoint of tutorial presented at SBS 2006)

  7. Screening Small Molecule Regulatory Enzymes: Glycosyltransferases, Sulfotransferases and Phosphotransferases

 

Transcreener® GDP Assay

  1. Selective Detection of LRRK2 GTPase Activity with the Transcreener® GDP Assay (SLAS 2013)
  2. Investigation of different GTPase classes with the Transcreener GDP Assay (SLAS 2012)

  3. Discovery of small molecule inhibitors for RGS proteins using the RGS screen Platform (SBS 2011)

  4. Targeting RGS Proteins using Engineered Galpha Proteins and the Transcreener® GDP Assay (SBS 2010)

  5. Engineering G alpha Proteins for Detection of RGS Protein GAP Activity with the Transcreener® GDP Assay (Screening Europe 2009)

  6. GDP Detection Using the Transcreener HTS Assay Technology (SBS 2008)

  7. An RGS Protein HTS Strategy using the Transcreener GDP Assay (SBS 2008)

 

Transcreener® UDP Assay

  1. Transcreener® High Throughput Screening Assays for Glycosyltransferases (SLAS 2013)
  2. Interrogating Diverse Target Families by Homogenous Immunodetection of Nucleotides (Glyco 2008)

  3. Homogenous UDP Detection: Applications in Glycobiology (Glyco 2007)
    Note: the following posters include data generated with the Transcreener UGT 488 Assay. This assay has been replaced by the Transcreener UDP far red Assay, which minimizes assay interference while adhering to our strict assay standards

  1. Screening Covalent Regulatory Enzymes: Glycosyltransferases, Sulfotransferases, (SBS 2006)

  2.  Phosphodiesterases and other Emerging Targets (powerpoint tutorial presented at SBS 2006)

 

Transcreener® EPIGEN Assays

  1. Profiling MT Inhibitors with Transzyme™ Methyltransferase Enzyme Assay Kits (SLAS 2013)
  2. Validation of  Transcreener® EPIGEN  Assays for Screening Chromatin Modifying Enzymes: Methylation and Acetylation (SLAS 2012)

  3. Automation of a Generic Fluorescence Methyl transferase activity assay (SLAS 2012)

  4. Development and validation of generic fluorescence methyltransferase assay using the Transcreener AMP GMP assay (SBS 2011)

  5. Development and validation of generic fluorescence acetyltransferase assay using the Transcreener AMP GMP assay (SBS 2011)