Biology at Work
Transcreener® Inside ...
Transcreener® EPIGEN Assays combine the extensively validated Transcreener® AMP/GMP Assay with coupling enzymes that convert the SAH produced in a Methyltransferase reaction to AMP.
- Universal Detection: Assays detect SAH, product common to all methyltransferase reactions.
- Homogenous Format: Simple mix-and-read format with Fluorescence Polarization readout.
- Sensitive: Detection of nanomolar SAH allows use of very low substrate concentrations.
Transcreener EPIGEN Methyltransferase Technical Manual
Transcreener EPIGEN Methyltransferase Posters and Presentations
Simple & HTS-Ready
The Transcreener® EPIGEN Assays are simple, HTS-ready and have the outstanding deck and signal stability that Transcreener® Assays are known for. Run your enzyme reaction, add the quench reagent, add detection reagents (coupling enzymes are pre-combined with Transcreener® reagents), and read your plates.
Detection of HMTs with the Transcreener® Epigen Methyltransferase Assay. Enzyme titrations of Set7/9, G9a, and Suv39H1 histone methyltransferases with SAM at the indicated concentrations and a Histone H3-derived peptide as acceptor substrate. Reactions were quenched and Transcreener® EPIGEN MT detection reagents were added.
| Product | Cat# | Quantity | Price | |
|---|---|---|---|---|
| Transcreener® EPIGEN Methyltransferase Assay | 3017-1K | 1000 assays (384 well format) | $975 |  |
| Transcreener® EPIGEN Acetyltransferase Assay | Coming Soon! | |||
For more information on the EPIGEN Methyltransferase Assay contact BellBrook Labs:
866.313.7881 in North America
info@bellbrook labs.com