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Category: Resources

Webinar: Streamline HTS and Lead Discovery with the Transcreener ADP Kinase Assay

Friday, 16 March 2018 by Bellbrook Labs
Identifying bona fide hits efficiently and effectively is a challenge in any small molecule drug discovery program. Using the appropriate assays for screening and hit-to-lead is an important determinant of success, but choosing from among the myriad types of assays can be a daunting process. ADP detection simplifies discovery, providing a universal approach to targeting
Transcreener ADP Kinase Assay
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  • Published in HTS Assays, Resources
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Another Tool for the HTS Toolbox: Two Additional Plate Readers Certified for Transcreener Assays

Wednesday, 30 November 2016 by Bellbrook Labs
Increased instrumentation costs and limited budgets mean that most HTS labs rely on a single type of multimode plate reader, which may limit the detection modes that can be used.  The ability of an assay technology to generate different types of readouts and perform well on a variety of plate readers is certainly an asset
HTS Assay Applications
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  • Published in Products, Resources
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New Case Study: Discovery of GALNT3 Inhibitors Using a Universal Glycosyltransferase Assay and Orthogonal Pooled Screening

Friday, 27 November 2015 by Bellbrook Labs
Glycosyltransferase (GT) enzymes participate in diverse metabolic and regulatory roles by catalyzing the transfer of sugars to protein, lipid and carbohydrate acceptors as well as to other molecules. Within the GT family, there are over 20 distinct polypeptide N-acetylgalactosaminyltransferases (GALNTs) that catalyze the initial step of O-glycosylation. GALNT3 overexpression and dysregulation has been directly linked
Assay Development ServicesTranscreener GDP Assay
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  • Published in News, Resources
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