Five Considerations When Choosing a Biochemical Assay Development Services CRO
Monday, 28 September 2020
There are many options out there for choosing assay development services, and finding what you need can be a challenging endeavor. Here we outline five items to look for when searching for the CRO that is right for your project. To narrow things down a bit, this article will focus on biochemical assay development services
- Published in Resources
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Webinar: Streamline HTS and Lead Discovery with the Transcreener ADP Kinase Assay
Friday, 16 March 2018
Identifying bona fide hits efficiently and effectively is a challenge in any small molecule drug discovery program. Using the appropriate assays for screening and hit-to-lead is an important determinant of success, but choosing from among the myriad types of assays can be a daunting process. ADP detection simplifies discovery, providing a universal approach to targeting
- Published in HTS Assays, Resources
Another Tool for the HTS Toolbox: Two Additional Plate Readers Certified for Transcreener Assays
Wednesday, 30 November 2016
Increased instrumentation costs and limited budgets mean that most HTS labs rely on a single type of multimode plate reader, which may limit the detection modes that can be used. The ability of an assay technology to generate different types of readouts and perform well on a variety of plate readers is certainly an asset
New Case Study: Discovery of GALNT3 Inhibitors Using a Universal Glycosyltransferase Assay and Orthogonal Pooled Screening
Friday, 27 November 2015
Glycosyltransferase (GT) enzymes participate in diverse metabolic and regulatory roles by catalyzing the transfer of sugars to protein, lipid and carbohydrate acceptors as well as to other molecules. Within the GT family, there are over 20 distinct polypeptide N-acetylgalactosaminyltransferases (GALNTs) that catalyze the initial step of O-glycosylation. GALNT3 overexpression and dysregulation has been directly linked