Here is what you may have missed…
- Learn about our new AptaFluor SAH Methyltransferase Assay
- Discuss which HTS assays might be a fit for your research
- Discover how BellBrook Labs’ services can help accelerate your drug discovery program
Targeting the cGAS-STING Pathway Using a Homogenous, HTS Compatible Transcreener® cGAS Assay
Thursday, September 28th – 12:20 PM
Aberrant activation of the DNA sensor cyclic GAMP synthase (cGAS) by self-DNA drives serious autoimmune diseases such as systemic lupus erythematosus. To accelerate discovery of cGAS inhibitors, we developed Transcreener-based assays for detecting cGAMP, which allow sensitive measurement of cGAS enzymatic activity with FP and TR-FRET signals.