BellBrook scientists will use their extensive biochemistry and enzymology expertise to identify actives from your virtual screen, prioritize your HTS hits, or generate quantitative data to drive your SAR/medicinal chemistry efforts.

We will work closely with you to define the specific parameters that are important for your lead discovery program and implement the most efficient and cost effective assays and/or kinetic analyses.

Lead Discovery Services Include:

Example Targets:

  • Protein Kinases
  • Lipid Kinases
  • Carbohydrate Kinases
  • ATPases
  • Methyltransferases
  • Acetyltransferases
  • HDACs
  • GTPases, GAPs, GEFs
  • Phosphodiesterases
  • Helicases
  • Ligases/Synthetases
  • Glycosyltransferases

Accelerating the Drug Discovery Process