AptaFluor® Biochemical Methyltransferase Assay Kit
Biochemical methyltransferase assay kits from BellBrook Labs provide a simple tool for measuring methyltransferase activity in a high throughput format. The assay uses an aptamer that selectively binds to SAH, the product of SAM-dependent methyltransferase reactions. The aptamer is split into two individually labeled pieces that come together only in the presence of SAH. Upon binding, a positive TR-FRET signal can be measured which enables screening and profiling of slow, low turnover methyltransferases with a simple biochemical assay.
Direct Detection of SAH Enables a Universal Assay Method for Methyltransferases
Enter your contact info and learn how the ultra-sensitive AptaFluor assay can be used for methyltransferase lead discovery!
* We will never share your contact info with anyone but we may send an e-mail or two per month about exciting news in drug discovery.