BellBrook Labs
1232 Fourier Drive, Suite 115
Madison, Wisconsin 53717 USA
(608) 443-2400
info@bellbrooklabs.com
Showing 1–9 of 27 results
The TREX1 Assay System used with Transcreener’s dAMP Exonuclease Assay (sold separate) directly measures dAMP produced by TREX1 as it cleaves polynucleotides. The TREX1 assay system includes the TREX1 enzyme, DNA substrate, assay plates and buffer components required to measure TREX1 activity. This kit contains components for 100,000 assay wells in a 384-well format. The Transcreener dAMP Exonuclease Assay is not included in the assay system but is available for separate purchase through BellBrook Labs. The Transcreener dAMP exonuclease assay is designed for HTS, Hit-to-Lead, SAR, and general discovery and can be used with any plate reader that measures fluorescence polarization.
The TREX1 Assay System used with Transcreener’s dAMP Exonuclease Assay (sold separate) directly measures dAMP produced by TREX1 as it cleaves polynucleotides. The TREX1 assay system includes the TREX1 enzyme, DNA substrate, assay plates, and buffer components required to measure TREX1 activity. This kit contains components for 10,000 assay wells in a 384-well format. The Transcreener dAMP Exonuclease Assay is not included in the assay system but is available for separate purchase through BellBrook Labs. The Transcreener dAMP exonuclease assay is designed for HTS, Hit-to-Lead, SAR, and general discovery and can be used with any plate reader that measures fluorescence polarization.
The TREX1 Assay System used with Transcreener’s dAMP Exonuclease Assay (sold separate) directly measures dAMP produced by TREX1 as it cleaves polynucleotides. The TREX1 assay system includes the TREX1 enzyme, DNA substrate, assay plates and buffer components required to measure TREX1 activity. This kit contains components for 1,000 assay wells in a 384-well format. The Transcreener dAMP Exonuclease Assay is not included in the assay system but is available for separate purchase through BellBrook Labs. The Transcreener dAMP exonuclease assay is designed for HTS, Hit-to-Lead, SAR, and general discovery and can be used with any plate reader that measures fluorescence polarization.
The CD38 Assay System includes CD38 enzyme, NAD+, assay plates, and buffers required for a CD38 reaction to produce ADPR. The Transcreener ADPR Assay (sold separately) uses coupling enzyme to convert ADPR to AMP, which is then detected using a far-red, competitive assay to measure enzymatic activity. This kit contains components for 100,000 assay wells in a 384-well format. The Transcreener ADPR Assay is not included in the assay system but is available for separate purchase through BellBrook Labs. The Transcreener ADPR assay is designed for HTS, Hit-to-Lead, SAR, and general discovery.
The CD38 Assay System includes CD38 enzyme, NAD+, assay plates, and buffers required for a CD38 reaction to produce ADPR. The Transcreener ADPR Assay (sold separately) uses coupling enzyme to convert ADPR to AMP, which is then detected using a far-red, competitive assay to measure enzymatic activity. This kit contains components for 10,000 assay wells in a 384-well format. The Transcreener ADPR Assay is not included in the assay system but is available for separate purchase through BellBrook Labs. The Transcreener ADPR assay is designed for HTS, Hit-to-Lead, SAR, and general discovery.
The CD38 Assay System includes CD38 enzyme, NAD+, assay plates, and buffers required for a CD38 reaction to produce ADPR. The Transcreener ADPR Assay (sold separately) uses coupling enzyme to convert ADPR to AMP, which is then detected using a far-red, competitive assay to measure enzymatic activity. This kit contains components for 1,000 assay wells in a 384-well format. The Transcreener ADPR Assay is not included in the assay system but is available for separate purchase through BellBrook Labs. The Transcreener ADPR assay is designed for HTS, Hit-to-Lead, SAR, and general discovery.
The WRN Helicase ATPase Assay System includes enzyme, substrate, assay plates, and buffers required for a WRN helicase reaction to produce ADP. The Transcreener ADP FI Assay (sold separately) is a far-red, competitive assay that directly measures ADP production to determine enzymatic activity with a fluorescence intensity (FI) readout. This kit contains components for 100,000 assay wells in a 384-well format. The Transcreener ADP FI Assay is not included in the assay system but is available for separate purchase through BellBrook Labs. The Transcreener ADP assay is designed for HTS, Hit-to-Lead, SAR, and general discovery.
The WRN Helicase ATPase Assay System includes enzyme, substrate, assay plates, and buffers required for a WRN helicase reaction to produce ADP. The Transcreener ADP FP Assay (sold separately) is a far-red, competitive assay that directly measures ADP production to determine enzymatic activity with a fluorescence polarization (FP) readout. This kit contains components for 100,000 assay wells in a 384-well format. The Transcreener ADP FP Assay is not included in the assay system but is available for separate purchase through BellBrook Labs. The Transcreener ADP assay is designed for HTS, Hit-to-Lead, SAR, and general discovery.
The WRN Helicase ATPase Assay System includes enzyme, substrate, assay plates, and buffers required for a WRN helicase reaction to produce ADP. The Transcreener ADP TR-FRET Assay (sold separately) is a far-red, competitive assay that directly measures ADP production to determine enzymatic activity with a Time-Resolved Förster Resonance Energy Transfer (TR-FRET) readout. This kit contains components for 100,000 assay wells in a 384-well format. The Transcreener ADP TR-FRET Assay is not included in the assay system but is available for separate purchase through BellBrook Labs. The Transcreener ADP assay is designed for HTS, Hit-to-Lead, SAR, and general discovery.