Active, full-length (aa 1-976), human poly(ADP-Ribose) glycohydrolase (PARG) enzyme, C-terminal 6xHis-tagged protein expressed and purified from Baculovirus-infected insect cells. The enzyme has been thoroughly validated with Transcreener ADPR Activity Assays. For specific activity, please refer to the Certificate of Analysis for each individual enzyme lot. Purity is >80% in a 50 mM Tris (pH 7.5), 500 mM NaCl, 10% glycerol, and 1 mM TCEP composition. Currently used with the Transcreener assay at a concentration between 5.3 - 6.1 pM in a 10 μL reaction.