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Tag: Assay Development Services

RGS4 Inhibitor Shows Activity in Parkinson’s Disease Model

Thursday, 18 June 2015 by Robert Lowery
RGS (regulator of G-protein signaling) proteins attenuate GPCR signals and provide an intriguing alternative to direct receptor targeting for modulating GPCR pathways. A recent effort led by Richard Neubig at Michigan State University (Blazer, et al ACS Chem Neurosci. 2015 Apr 20) provides a big boost to validation of RGS proteins as drug targets. Their
Assay Development Services
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  • Published in Neurodegenerative Diseases
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NEW! Orthogonal Pooled Screening – 5X Higher Efficiency, 80% Fewer Resources

Wednesday, 15 April 2015 by Edna.Kunkel
Do what you’re good at with 5-fold greater efficiency—and leave the rest to us. We are pleased to announce that BellBrook Labs is partnering with the Lankenau Institute for Medical Research (LIMR) to provide access to an innovative Orthogonal Pooled Screening (OPS™) Platform. The OPS™ Platform provides drug discovery researchers with a drastically more efficient
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  • Published in News
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BellBrook Labs Launches HTS Assay Platform for Targeting GPCR Regulatory Proteins

Tuesday, 09 October 2012 by Robert Lowery
BellBrook Labs launched a comprehensive HTS assay reagent platform for “Regulators of G-protein Signaling” (RGS) protein, a family of proteins that shows promise as drug targets because of their emerging role in regulating G Protein-Coupled Receptors (GPCRs).  The proprietary RGScreen technology, which combines kinetically enhanced recombinant proteins with BellBrook’s Transcreener GDP Assay, opens up new
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  • Published in Emerging Targets
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