Using a Universal GMP Assay for PDE Research

GMP Assay for PDE Inhibitor Discovery
A universal GMP assay to aid in PDE research and potential COVID-19 disruption. – Phosphodiesterase enzymes (PDEs) modulate pathways throughout the body. Since unregulated PDEs contribute to disease in many cases, it makes sense therapies that inhibit these enzymes have the potential to treat several different ailments. These include cardiovascular and respiratory issues, diabetes, fibrotic
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How A PDE Activity Assay Might Help Find New Treatments for Individuals Suffering from Heart Disease

PDE Activity Assay Heart Disease
Heart Disease: The Role of PDEs and a PDE Activity Assay Heart disease is often misunderstood due to confusion with terminology and the different types of heart disease that exist. While a heart attack can occur quickly, heart failure is a slower progression where the heart weakens over time. One thing is certain; heart disease
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Could an Inhibitor of Phosphodiesterase Activity be a Treatment for Alzheimer’s?

As we continue to increase our lifespan, diseases such as Alzheimer’s will subsequently persist to develop. With up to 4.5 million Americans currently affected, there’s a strong desire to find a cure or at the very least some relief from the symptoms.¹   Neurodegeneration derived memory loss is the most common and perhaps the most devastating result
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