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Tag: PRMT5

PRMT5 is Innately Interesting

Wednesday, 30 March 2022 by Bellbrook Labs
PRMT5 Role with Macrophages
PRMT5 is a type II arginine methyltransferase that dimethylates arginine residues symmetrically. Its various functions extend into T cell development, B cell regulation, hematopoiesis, and mitotic control. In the past, research on PRMT5 primarily focused on cancer and the adaptive immune response. These are both situations where metabolism and growth are critical. Recent reports implicate
AptaFluor SAH Methyltransferase AssayLead Discovery ServicesPRMT5
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  • Published in Emerging Targets, Epigenetics, Innate Immunity
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Digging into Dopamine Signaling: Arginine Methylation Regulates GPCRs

Monday, 25 January 2016 by Robyn Perrin
The neurotransmitter dopamine is one of the most fascinating substances regulating behavior, with both delightful and dark qualities. Affecting a mere 20,000 dopamine-responsive neurons out of 100 billion neurons in the human brain, dopamine nonetheless governs critical aspects of our existence including voluntary movement, psychosis, and addiction. Disrupted dopamine signaling is involved in maladies ranging
AptaFluor SAH Methyltransferase Assaydopamine receptor signalingEPIGEN Methyltransferase AssayG protein-coupled receptorsGPCRmethyltransferasePRMT5
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  • Published in Emerging Targets
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