Posters and Presentations

Transcreener ADP2 Assay

  1. Targeting Kinases Involved in Innate Immunity with Transcreener ADP Assay  (SLAS 2021)
  2. The Transcreener ADP² Assay: A Universal Kinase Assay for HTS and Lead Optimization (DOT 2018)
  3. The Transcreener ADP² Assay: A Universal Kinase Assay for Both HTS and Lead Discovery (SLAS 2017)
  4. Determination of Drug Residence Times in a HTS format using Kinetic Analysis with the Transcreener ADP2 Assay (SLAS 2016)
  5. Transcreener ADP2 Assays: Simplifying and Streamlining Kinase Profiling from Experimental Design through Data Analysis (SLAS 2016)
  6. Determination of Drug Residence Time in an HTS Format using Kinetic Analysis with the Transcreener ADP2 Assay (DOT 2015)
  7. Transcreener ADP2 Assay: Simplifying and Streamlining Kinase Profiling from Experimental Design through Data Analysis (SLAS 2014)
  8. Comparison of ADP Detection Methods used for High Throughput Screening (SLAS 2013)
  9. Transcreener ADP2Assays: Streamlining Inhibitor Profiling for Kinases with Diverse ATP Requirements (MIPTEC 2010)
  10. ADP Detection in FP, TR-FRET and FI Assay Formats: Versatile Kinase/ATPase Detection Without the Use of Coupling Enzymes (SBS 2010)
  11. ADP Detection in FP, TR-FRET and FI Assay Formats: Versatile Kinase/ATPase Detection without the Use of Coupling Enzymes (Screening Europe, 2010)
  12. Utility of Hybrid Multi-Mode Readers using Both Monochromator- and Filter-Based Detection Capabilities as Demonstrated with Fluorescence Polarization, Time-Resolved Fluorescence Resonance Energy Transfer, and Fluorescence Intensity Assays for the Measurement of ADP (Lab Auto 2010)
  13. Improved Versatility of the Transcreener ADP2 Assay: Alternative Fluorescence Detection Modes for All Major Instrument Platforms (Protein Kinase Target, 2009)
  14. Transcreener ADP2 TR-FRET Red Assay: Homogeneous ADP Detection (SBS 2009)
  15. Targeting Low Activity ATP-utilizing Enzymes with the Improved Transcreener ADP2 FP Assay (SBS 2009)
  16. Detecting ATP-utilizing Enzyme Activity Using a Simple Fluorescence Intensity Quenching ADP Assay (SBS 2009)
  17. Robust Detection of ATP-Utilizing Enzymes with an Improved Fluorescence Polarization ADP Detection Assay (Screening Europe 2009)
  18. Volume Scaling of the Transcreener ADP2 FP Assay on the BioTek Synergy™ 2 and 4 Multi-Mode Microplate Readers Allows For Easy Transition From Assay Development to High-Throughput Screening (ALA 2009)
  19. Generating Better Biology Through the Use of BellBrook Labs’ Transcreener ADP2 FP Assay and the BMG LABTECH PHERAstar Plus (ALA 2009)
  20. Demonstration of the Next Generation Transcreener ADP2 FP Assay on the Tecan Safire2™ Microplate Reader (ALA 2009)
  21. Generate Improved Fluorescence Polarization Screening Results on PerkinElmer’s EnVision® Microplate Reader Through the Use of the Transcreener ADP2 FP Assay (ALA 2009)

Transcreener ADP Assay

  1. Beyond Kinases: Interrogating the Purinome (Keystone 2010)
  2. Optimizing Performance of the Transcreener ADP Assay for Commonly Used Multiwell Readers (SBS 2008)
  3. Application of the Transcreener Kinase Assay Platform in Evaluating PI3 Lipid Kinases (SBS 2007)
  4. Expanding Transcreener Assay Technology: ADP Detection using TR-FRET
  5. Interrogating Diverse Target Families by Homogenous Immunodetection of Nucleotides (Glyco 2007)
  6. Interrogation of Protein Phosporylation, Ubiquitination and Sumoylation Pathways Using Adenine Nucleotide Detection Assay (Cell Signaling 2007)
  7. ADP Detection Assay for Diverse Kinases and ATPases
  8. A Robust and Flexible HTS Kinase Assay Using ADP Detection
  9. Simplifying Kinase Profiling using ADP Detection with the Transcreener Kinase Assay
  10. Screening Covalent Regulatory Enzymes: Glycosyltransferases, Sulfotransferases, Phosphodiesterases and other Emerging Targets (tutorial presented at SBS 2006)

Transcreener AMP/GMP Assay

  1. Targeting ENPP1 for Cancer Immunotherapy: Development of an HTS Method Using the Transcreener® AMP²/GMP² Assay
  2. Development of a High Throughput Transcreener Assay to Explore the Ectonucleotidase Enzyme Family. (SLAS 2019)
  3. Targeting CD39: A High Throughput Ectonucleotidase Assay Based on the Transcreener AMP/GMP Assay (DOT 2017)
  4. TR-FRET Based Transcreener AMP/GMP Assay for Screening Ligases, Synthetases and Phosphodiesterases (SLAS 2016)
  5. TR-FRET Based Transcreener AMP/GMP Assay for Screening Ligases, Synthetases and Phosphodiesterases (SLAS 2014)
  6. Monitoring flux through the Sumoylation pathway using the Transcreener AMP/GMP assay (Keystone 2009)
  7. Application of the Transcreener AMP/GMP Assay for Interrogating Ubiquitinylation Cascades (SBS 2008)
  8. Homogenous AMP and GMP Detection : Applications in Drug Discovery (SBS 2007)
  9. Interrogation of Protein Phosporylation, Ubiquitination and Sumoylation Pathways Using Adenine Nucleotide Detection Assay (Cell Signaling 2007)
  10. Transcreener PDE Assay: Homogenous AMP and GMP Detection
  11. Screening Covalent Regulatory Enzymes: Glycosyltransferases, Sulfotransferases, Phosphodiesterases and other Emerging Targets (tutorial presented at SBS 2006)
  12. Screening Small Molecule Regulatory Enzymes: Glycosyltransferases, Sulfotransferases and Phosphotransferases

Transcreener cGAMP Assay

  1. Enabling Discovery of cGAS Antagonists with the Transcreener® cGAS Assay (SLAS 2020)
  2. Targeting cGAS for Type 1 Interferon-Driven Autoimmune Diseases (SLAS 2019)
  3. Targeting the cGAS-STING Pathway Using a Homogenous, HTS Compatible Transcreener cGAS Assay (SLAS 2018)

Transcreener GDP Assay

  1. A Homogenous, High-Throughput Assay to Measure Guanine Nucleotide Exchange Factor Activity Using Transcreener GDP Assay (SLAS 2017)
  2. Interrogation of Modulators of GPCR and small GTPase Activity: Screening GAPs and GEFs with the Transcreener GDP Assay (SLAS 2016)
  3. Interrogation of Modulators of GPCR and small GTPase Activity: Screening GAPs and GEFs with the Transcreener GDP Assay (DOT 2015)
  4. A High Throughput Assay for Rho Guanine Nucleotide Exchange Factors Based on the Transcreener GDP Assay (FASEB Small GTPases 2015)
  5. Selective Detection of LRRK2 GTPase Activity with the Transcreener GDP Assay (SLAS 2013)
  6. Investigation of different GTPase classes with the Transcreener GDP Assay (SLAS 2012)
  7. Discovery of small molecule inhibitors for RGS proteins using the RGS screen Platform (SBS 2011)
  8. Targeting RGS Proteins using Engineered Galpha Proteins and the Transcreener GDP Assay (SBS 2010)
  9. Engineering G alpha Proteins for Detection of RGS Protein GAP Activity with the Transcreener GDP Assay (Screening Europe 2009)
  10. GDP Detection Using the Transcreener HTS Assay Technology (SBS 2008)
  11. An RGS Protein HTS Strategy using the Transcreener GDP Assay (SBS 2008)

Transcreener UDP Assay

  1. A Universal Mix-and-Read Transcreener UDP FI Glycosyltransferase Assay to Study GALNT Activity (SLAS 2021)
  2. Discovery of Inhibitors of GALNT3 by Orthogonal Pooled Screening with a Universal Glycosyltransferase Assay (SLAS 2016)
  3. Discovery of Inhibitors of GALNT3 by Orthogonal Pooled Screening with a Universal Glycosyltransferase Assay (Glyco 2015)
  4. Development of a Homogenous Transcreener UDP2 TR-FRET Assay for High Throughput Screening of Glycosyltransferases (DDD 2015)
  5. Screening Diverse Glycosyltransferases Using Homogenous, Fluorescent Transcreener HTS Assays For Direct Detection of Nucleotide Products (SLAS 2014)
  6. Transcreener High Throughput Screening Assays for Glycosyltransferases (SLAS 2013)
  7. Interrogating Diverse Target Families by Homogenous Immunodetection of Nucleotides (Glyco 2008)
  8. Homogenous UDP Detection: Applications in Glycobiology (Glyco 2007)
    Note: the following posters include data generated with the Transcreener UGT 488Assay. This assay has been replaced by the Transcreener UDP far red Assay, which minimizes assay interference while adhering to our strict assay standards
  9. Screening Covalent Regulatory Enzymes: Glycosyltransferases, Sulfotransferases (SBS 2006)
  10. Phosphodiesterases and other Emerging Targets (tutorial presented at SBS 2006)

Transcreener EPIGEN Assay

  1. Interrogating Chromatin Modifying Enzymes: Methyltransferases, Acetyltransferases, Kinases and SUMO ligases Using Transcreener Assays (SLAS 2016)
  2. Optimization of Enzyme Reactions for Screening and Profiling Wild Type EZH2 with the Transcreener EPIGEN Methyltransferase Assay (SLAS 2014)
  3. Profiling MT Inhibitors with Transzyme™ Methyltransferase Enzyme Assay Kits (SLAS 2013)
  4. Validation of Transcreener EPIGEN  Assays for Screening Chromatin Modifying Enzymes: Methylation and Acetylation (SLAS 2012)
  5. Automation of a Generic Fluorescence Methyl transferase activity assay (SLAS 2012)
  6. Development and validation of generic fluorescence methyltransferase assay using the Transcreener AMP GMP assay (SBS 2011)
  7. Development and validation of generic fluorescence acetyltransferase assay using the Transcreener AMP GMP assay (SBS 2011)

Transcreener ADO CD73 Assay

  1. Transcreener CD73 Assay: A High Throughput, Sensitive Assay to Measure Adenosine (SLAS 2020)

Transcreener 2-5A OAS Assay

  1. Targeting OAS Enzymes with the Transcreener 2-5A OAS Assay (SLAS 2022)

Transcreener dAMP Exonuclease Assay

  1. Interrogating Trex1 with the Transcreener dAMP Exonuclease Assay (SLAS 2023)

Transcreener ADPR Assay

  1. Interrogating CD38 and PARG with the Transcreener ADPR Assay (SLAS 2023)

AptaFluor SAH Methyltransferase Assay

  1. Sensitive Detection of PRMT4 using Physiological SAM with the AptaFluor® Methyltransferase Assay (SLAS 2019)
  2. AptaFluor SAH: A Homogenous, Universal Methyltransferase Assay Based on a Microbial Riboswitch (DOT 2017)
  3. A Homogeneous, Universal Enzymatic Assay for Histone Methyltransferases Based on a Microbial Riboswitch (DOT 2016)

BellBrook Labs
1232 Fourier Drive, Suite 115
Madison, Wisconsin 53717 USA
(608) 443-2400

info@bellbrooklabs.com

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